Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.69 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529582 | 0.92 | PTGDR2 (0.80) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529300 | 0.91 | PTGDR2 (0.72) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6533995 | 0.90 | PTGDR2 (0.73) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6531254 | 0.88 | PTGDR2 (0.60) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6532744 | 0.88 | PTGDR2 (0.86) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529040 | 0.85 | PTGDR2 (0.73) | PTGDR2PTGDRCCKAR | |
| SCHEMBL6532747 | 0.84 | PTGDR2 (0.73) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6529665 | 0.84 | PTGDR2 (0.64) | PTGDR2PTGDR | |
| SCHEMBL6531237 | 0.83 | PTGDR2 (0.68) | PTGDR2PTGDRAKR1C3AKR1C2CCKAR | |
| SCHEMBL6531329 | 0.82 | PTGDR2 (1.00) | PTGDR2PTGDRAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040112-A1 | COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY | OXAGEN LIMITED (GB) | 2005-05-06 | — | — | WO | disclosed |