Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.45 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511976 | 0.84 | DPP4 (0.54) | S1PR1SCD5HCRTR1HCRTR2TSHR | |
| SCHEMBL6528825 | 0.82 | USP30 (0.47) | USP30UCHL1EPHX2KDM4EPOLB | |
| SCHEMBL6527845 | 0.78 | DPP4 (0.61) | USP30UCHL1KDM4EPOLBTSHR | |
| SCHEMBL6529820 | 0.77 | DPP4 (0.47) | S1PR1SCD5HCRTR1HCRTR2TSHR | |
| SCHEMBL6533019 | 0.77 | DPP4 (0.61) | USP30UCHL1EPHX2KDM4EPOLB | |
| SCHEMBL17064042 | 0.77 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL17064040 | 0.77 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL16465832 | 0.76 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL16465831 | 0.76 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL6532079 | 0.76 | HSD17B10 (0.47) | USP30UCHL1KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |