Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532596 | 1.00 | KMT2A (0.36) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1480804 | 0.88 | MAPT (0.41) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1480802 | 0.88 | MAPT (0.41) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1480461 | 0.86 | MAPT (0.41) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1480463 | 0.86 | MAPT (0.41) | KMT2AMEN1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1480642 | 0.85 | MEN1 (0.45) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1480644 | 0.85 | MEN1 (0.45) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1480230 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2TP53APPTRPV1 | |
| SCHEMBL1480232 | 0.83 | MAPT (0.43) | MAPTSMN1; SMN2TP53APPTRPV1 | |
| SCHEMBL1482165 | 0.82 | MAPT (0.42) | KMT2AMEN1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |