Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 5/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310167 | 0.84 | S1PR1 (0.39) | S1PR1S1PR3S1PR5S1PR4LPAR3 | |
| SCHEMBL8967122 | 0.84 | TSHR (0.38) | S1PR1S1PR3S1PR5S1PR4TSHR | |
| SCHEMBL8054267 | 0.80 | TSHR (0.34) | TSHRCYP2C19 | |
| SCHEMBL18893736 | 0.79 | CETP (0.33) | S1PR1S1PR3S1PR5S1PR4LPAR3 | |
| SCHEMBL9018612 | 0.78 | TYMS (0.42) | LPAR3LPAR2TSHRCYP2C19 | |
| SCHEMBL8161690 | 0.77 | TSHR (0.44) | TSHRCYP2C19 | |
| SCHEMBL21995390 | 0.77 | LPAR3 (0.33) | S1PR1S1PR3S1PR5S1PR4LPAR3 | |
| Phosphoric Acid SCHEMBL29210836 | 0.77 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4LPAR3 | |
| SCHEMBL11030099 | 0.72 | SMPD1 (0.42) | S1PR1S1PR3S1PR5S1PR4LPAR3 | |
| Tetradecane SCHEMBL28597707 | 0.71 | LPAR3 (0.59) | LPAR3LPAR2FDPSLPAR1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050050594-A1 | Tryptophan synthase as a site of herbicide action | RODAWAY SHIRLEY (US) | 2005-03-03 | — | — | US | disclosed |
| EP-1144672-A3 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000046394-A9 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID CO (US) | 2001-10-18 | — | — | WO | disclosed |
| EP-1144672-A2 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000046394-A2 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANMID COMPANY (US) | 2000-08-10 | — | — | WO | disclosed |