Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.89 |
| ▸ | HDAC8 | Q9BY41 | 20/20 | 0.89 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532814 | 1.00 | HDAC1 (0.89) | HDAC1HDAC8HDAC6 | |
| SCHEMBL6532812 | 1.00 | HDAC1 (0.89) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560902 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560896 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5566777 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5566770 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5560899 | 0.94 | HDAC1 (1.00) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565872 | 0.94 | HDAC1 (0.88) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565876 | 0.94 | HDAC1 (0.88) | HDAC1HDAC8HDAC6 | |
| SCHEMBL5565871 | 0.94 | HDAC1 (0.88) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608628-A2 | HISTONE DEACETYLASE INHIBITORS | Takeda San Diego, Inc. (US) | 2005-12-28 | — | — | EP | claimed |
| WO-2004082638-A2 | HISTONE DEACETYLASE INHIBITORS | SYRRX, INC. (US) | 2004-09-30 | — | — | WO | claimed |