Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533252 | 1.00 | DPP4 (0.56) | DPP4DPP8DPP7LMNARAB9A | |
| SCHEMBL6532733 | 0.93 | DPP4 (0.54) | DPP4DPP8DPP7LMNARAB9A | |
| SCHEMBL6531563 | 0.88 | DPP4 (0.70) | DPP4DPP8DPP7DPP9CNR1 | |
| SCHEMBL6529872 | 0.86 | DPP4 (0.71) | DPP4DPP8DPP7 | |
| SCHEMBL6531187 | 0.81 | DPP4 (0.57) | DPP4DPP8DPP7LMNARAB9A | |
| SCHEMBL6530776 | 0.80 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL6529051 | 0.79 | DPP4 (0.49) | DPP4DPP8DPP7SMN1; SMN2 | |
| SCHEMBL6529052 | 0.79 | DPP4 (0.49) | DPP4DPP8DPP7SMN1; SMN2 | |
| SCHEMBL6531569 | 0.79 | DPP4 (0.82) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL6527898 | 0.78 | DPP4 (0.50) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |