SCHEMBL6533554

SCHEMBL6533554

C#CC[CH]C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL518032 0.72
Methane SCHEMBL28323479 0.69
SCHEMBL4665781 0.69
SCHEMBL931350 0.67
SCHEMBL27567861 0.67
SCHEMBL6477842 0.65
SCHEMBL7782391 0.63
SCHEMBL9280296 0.63
SCHEMBL28091555 0.63
SCHEMBL9799389 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938470-A1 AQUEOUS SYNTHESIS OF IODOPROPARGYL CARBAMATE Troy Technology Corporation, Inc. (US) 1999-09-01 EP claimed
WO-1998018756-A1 AQUEOUS SYNTHESIS OF IODOPROPARGYL CARBAMATE TROY CORPORATION (US) 1998-05-07 WO claimed
US-4246413-A ANALGESICS, ANTITUSSIVE AGENT, AND NARCOTICS ANTAGONIST BRISTOL-MYERS COMPANY (US) 1981-01-20 US claimed
US-4132740-A Preparation of carboranyl sulfides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1979-01-02 US claimed
US-11964938-B2 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists CELON PHARMA S.A. (PL) 2024-04-23 US disclosed
EP-3737470-B9 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2024-03-13 EP disclosed
CN-111757770-B 3-Phenyl-4-hexynoic acid derivatives as GPR40 agonists 赛隆制药股份公司 2023-10-03 CN disclosed
EP-3737470-B1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2022-12-14 EP disclosed
US-20200399198-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2020-12-24 US disclosed
EP-3737470-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2020-11-18 EP disclosed
CN-111757770-A 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists 赛隆制药股份公司 2020-10-09 CN disclosed
WO-2019134984-A1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS CELON PHARMA S.A. (PL) 2019-07-11 WO disclosed
EP-0912487-A1 SUBSTITUTED OXOBUTYRIC ACIDS AS MATRIX METALLOPROTEASE INHIBITORS Bayer Corporation (US) 1999-05-06 EP disclosed
WO-1998018756-A1 AQUEOUS SYNTHESIS OF IODOPROPARGYL CARBAMATE TROY CORPORATION (US) 1998-05-07 WO disclosed
CN-1176960-A Novel ester compounds, pesticidal compositions containing same and intermediates for synthesis thereof SUMITOMO CHEMICAL CO (JP) 1998-03-25 CN disclosed
WO-1997043238-A9 SUBSTITUTED OXOBUTYRIC ACIDS AS MATRIX METALLOPROTEASE INHIBITORS 1998-03-05 WO disclosed
US-5693849-A Aqueous synthesis of iodopropargyl carbamate TROY CORPORATION (US) 1997-12-02 US disclosed
WO-1997043238-A1 SUBSTITUTED OXOBUTYRIC ACIDS AS MATRIX METALLOPROTEASE INHIBITORS BAYER CORPORATION (US) 1997-11-20 WO disclosed
US-4360465-A PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
US-3773797-A PROPARGYL ALKYL OR ALKENYL ETHERS AND ESTERS CIBA-GEIGY CORPORATION, A CORP. OF NY 1973-11-20 US disclosed