Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511336 | 1.00 | PIM1 (0.47) | PIM1PIM2CYP2D6LMNACYP1A2 | |
| SCHEMBL6511842 | 0.91 | PIM1 (0.50) | PIM1PIM2MTORPIM3RAB9A | |
| SCHEMBL6511845 | 0.91 | PIM1 (0.50) | PIM1PIM2MTORPIM3RAB9A | |
| SCHEMBL6533562 | 0.86 | PIM1 (0.49) | PIM1PIM2CYP2D6LMNACYP1A2 | |
| SCHEMBL6514244 | 0.86 | PIM1 (0.49) | PIM1PIM2CYP2D6LMNACYP1A2 | |
| SCHEMBL6512061 | 0.81 | PIM1 (0.45) | PIM1PIM2NPSR1TSHRMTOR | |
| SCHEMBL6512065 | 0.81 | PIM1 (0.45) | PIM1PIM2NPSR1TSHRMTOR | |
| SCHEMBL6514075 | 0.77 | PIM1 (0.55) | PIM1PIM2CYP3A4MEN1KMT2A | |
| SCHEMBL6507601 | 0.77 | PIM1 (0.55) | PIM1PIM2CYP3A4MEN1KMT2A | |
| SCHEMBL6530093 | 0.75 | PIM1 (0.45) | PIM1PIM2MTORPIM3IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |