Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061679 | 0.84 | PPARA (0.39) | MAPTTP53CLK1LMNAPPARA | |
| SCHEMBL3067397 | 0.77 | MAPT (0.37) | MAPTTP53LMNAPPARAMEN1 | |
| SCHEMBL6311345 | 0.72 | MAPT (0.43) | MAPTTP53LMNAPPARAMEN1 | |
| SCHEMBL6309522 | 0.70 | MAPT (0.38) | MAPTLMNAPPARAMEN1ALDH1A1 | |
| SCHEMBL3061593 | 0.70 | ADRB3 (0.36) | MAPTLMNAPPARAMEN1ALDH1A1 | |
| SCHEMBL3101528 | 0.69 | CNR2 (0.43) | MAPTLMNAPPARAMEN1ALDH1A1 | |
| SCHEMBL3069248 | 0.69 | CNR2 (0.37) | MAPTLMNAMEN1ALDH1A1HTT | |
| SCHEMBL3069012 | 0.65 | FFAR1 (0.47) | MAPTMEN1HTTKMT2A | |
| SCHEMBL13817475 | 0.64 | MAPT (0.39) | MAPTLMNAPPARAMEN1ALDH1A1 | |
| SCHEMBL3097111 | 0.64 | MAPT (0.39) | MAPTLMNAPPARAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005123727-A1 | 3-ARYL-3-HYDROXY- AND 3-ARYL-3-OXOPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-29 | — | — | WO | disclosed |