Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 9/20 | 0.39 |
| ▸ | NR0B2 | Q15466 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533921 | 1.00 | ITGB2 (0.42) | ITGB2ICAM1ITGALEPRS1DHODH | |
| SCHEMBL1481016 | 0.95 | ITGB2 (0.46) | ITGB2ICAM1ITGALPTPN11NR0B2 | |
| SCHEMBL1481017 | 0.95 | ITGB2 (0.46) | ITGB2ICAM1ITGALPTPN11NR0B2 | |
| SCHEMBL1481013 | 0.95 | ITGB2 (0.46) | ITGB2ICAM1ITGALPTPN11NR0B2 | |
| SCHEMBL6530448 | 0.91 | ITGB2 (0.48) | ITGB2ICAM1ITGALPTPN11NR0B2 | |
| Cinnamic Acid SCHEMBL6471321 | 0.88 | ITGB2 (0.44) | ITGB2ICAM1ITGALPTPN11NR0B2 | |
| SCHEMBL1480157 | 0.87 | DHODH (0.39) | DHODHKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1480155 | 0.87 | DHODH (0.39) | DHODHKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1481731 | 0.85 | SMN1; SMN2 (0.52) | DHODHKDM4ENPC1CRHBPRAB9A | |
| SCHEMBL1481728 | 0.85 | SMN1; SMN2 (0.52) | DHODHKDM4ENPC1CRHBPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |