Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 16/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533991 | 0.92 | CCR9 (0.54) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL33250 | 0.90 | CCR9 (0.63) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL27682 | 0.82 | CCR9 (0.79) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344197 | 0.81 | CCR9 (0.74) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL12359421 | 0.80 | CCR9 (0.62) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL17395274 | 0.79 | CCR9 (0.66) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL28061 | 0.79 | CCR9 (0.63) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL29238 | 0.78 | CCR9 (0.64) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL27420 | 0.78 | CCR9 (0.68) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL27433 | 0.77 | CCR9 (0.74) | CCR9LMNAHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005112925-A1 | ARYL SULFONAMIDES | CHEMOCENTRYX (US) | 2005-12-01 | — | — | WO | disclosed |