Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 20/20 | 0.73 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | TEK | Q02763 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477687 | 0.90 | EPHB4 (0.86) | EPHB4KDRTEK | |
| SCHEMBL5477659 | 0.85 | EPHB4 (0.74) | EPHB4 | |
| SCHEMBL6529106 | 0.85 | EPHB4 (0.73) | EPHB4KDRTEK | |
| SCHEMBL5482878 | 0.85 | EPHB4 (1.00) | EPHB4KDRTEK | |
| SCHEMBL5475344 | 0.84 | EPHB4 (0.67) | EPHB4 | |
| SCHEMBL5482760 | 0.83 | EPHB4 (0.70) | EPHB4 | |
| SCHEMBL5478522 | 0.83 | EPHB4 (0.76) | EPHB4KDRTEK | |
| SCHEMBL5474469 | 0.83 | EPHB4 (0.65) | EPHB4 | |
| SCHEMBL5480217 | 0.83 | EPHB4 (0.84) | EPHB4KDRTEK | |
| SCHEMBL5483764 | 0.82 | EPHB4 (0.65) | EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019220-A9 | SUBSTITUTED IMIDAZO[1,2-A]PYRAZINES AS MODULATORS OF KINASE ACTIVITY | CELLULAR GENOMICS INC (US) | 2005-06-02 | — | — | WO | disclosed |