Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 2/20 | 0.53 |
| ▸ | ACP1 | P24666 | 6/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534374 | 1.00 | TACR3 (0.53) | TACR3ACP1SYK | |
| Hydrochloric Acid SCHEMBL6534588 | 0.99 | TACR3 (0.53) | TACR3ACP1SYK | |
| Hydrochloric Acid SCHEMBL6534586 | 0.99 | TACR3 (0.53) | TACR3ACP1SYK | |
| SCHEMBL6534306 | 0.95 | TACR3 (0.56) | TACR3ACP1SYK | |
| SCHEMBL6534314 | 0.95 | TACR3 (0.56) | TACR3ACP1SYK | |
| Hydrochloric Acid SCHEMBL6534629 | 0.94 | TACR3 (0.55) | TACR3ACP1SYK | |
| Hydrochloric Acid SCHEMBL6534632 | 0.94 | TACR3 (0.55) | TACR3ACP1SYK | |
| SCHEMBL6534428 | 0.91 | ACP1 (0.54) | TACR3ACP1 | |
| SCHEMBL6534431 | 0.91 | ACP1 (0.54) | TACR3ACP1 | |
| SCHEMBL17372662 | 0.91 | TACR3 (0.66) | TACR3ACP1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088818-B1 | Quinolin-4-yl derivatives | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | claimed |
| US-6440995-B1 | NMDA-RECEPTOR SUBTYPE SELECTIVE BLOCKERS | HOFFMAN-LA ROCHE INC. | 2002-08-27 | — | — | US | claimed |
| EP-1088818-A1 | Quinolin-4-yl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-04 | — | — | EP | claimed |
| EP-1088818-B1 | Quinolin-4-yl derivatives | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6440995-B1 | NMDA-RECEPTOR SUBTYPE SELECTIVE BLOCKERS | HOFFMAN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-1088818-A1 | Quinolin-4-yl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-04 | — | — | EP | disclosed |