Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534519 | 1.00 | TACR3 (0.72) | TACR3TACR2 | |
| SCHEMBL6534365 | 0.92 | TACR3 (0.62) | TACR3TACR2 | |
| SCHEMBL6534359 | 0.92 | TACR3 (0.62) | TACR3TACR2 | |
| SCHEMBL6534501 | 0.92 | TACR3 (0.62) | TACR3TACR2 | |
| SCHEMBL6534503 | 0.92 | TACR3 (0.62) | TACR3TACR2 | |
| SCHEMBL6534618 | 0.91 | TACR3 (0.61) | TACR3TACR2 | |
| SCHEMBL6534620 | 0.91 | TACR3 (0.61) | TACR3TACR2 | |
| SCHEMBL6534624 | 0.90 | DHODH (0.62) | TACR3 | |
| SCHEMBL6534623 | 0.90 | DHODH (0.62) | TACR3 | |
| SCHEMBL6534470 | 0.85 | USP2 (0.56) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983243-B1 | NOVEL QUINOLINE- AND NAPHTHALENECARBOXAMIDES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING CALPAIN | SMITHKLINE BEECHAM CORP (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6100267-A | ENZYME INHIBITOR FOR TREATMENT OF NEURODEGENERATIVE DISORDERS, STROKES, TRAUMATIC BRAIN INJURY, CATARACTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0983243-A1 | NOVEL QUINOLINE- AND NAPHTHALENECARBOXAMIDES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING CALPAIN | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998041506-A1 | NOVEL QUINOLINE- AND NAPHTHALENECARBOXAMIDES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF INHIBITING CALPAIN | SMITHKLINE BEECHAM CORPORATION (US) | 1998-09-24 | — | — | WO | disclosed |