Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585663 | 0.85 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL6310699 | 0.84 | TSHR (0.47) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL16424333 | 0.84 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10770471 | 0.84 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL20616615 | 0.82 | TSHR (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL6306577 | 0.82 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL24293924 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL29156594 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27458673 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27305517 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996705-A4 | ATTACHMENT OF UNMODIFIED NUCLEIC ACIDS TO SILANIZED SOLID PHASE SURFACES | BECKMAN COULTER INC (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6387626-B1 | SIMPLE AND COST EFFICIENT METHOD TO IMMOBILIZE UNMODIFIED NUCLEIC ACIDS BY COATING SOLID PHASE WITH SILANE, ALLOWING COATING TO CURE, THEN COUPLING NUCLEIC ACID MOLECULES HAVING TERMINAL HYDROXY GROUP | ORCHID BIOSCIENCES, INC. | 2002-05-14 | — | — | US | disclosed |
| EP-0996705-A1 | ATTACHMENT OF UNMODIFIED NUCLEIC ACIDS TO SILANIZED SOLID PHASE SURFACES | Orchid Biocomputer, Inc. (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5919626-A | SIMPLE AND COST EFFICIENT METHOD BY COATING SOLID PHASE WITH MERCAPTO-SILANE OR EPOXY-SILANE AND COUPLING UNMODIFIED 3' HYDROXY OR 5' HYDROXY TERMINAL NUCLEIC ACID TO SILANE | ORCHID BIO COMPUTER, INC. (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998055593-A1 | ATTACHMENT OF UNMODIFIED NUCLEIC ACIDS TO SILANIZED SOLID PHASE SURFACES | ORCHID BIOCOMPUTER, INC. (US) | 1998-12-10 | — | — | WO | disclosed |