Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.46 |
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL20544204 | 1.00 | PPARG (0.46) | PPARGPPARDPPARAGPR84HDAC11 | |
| Palmitic Acid SCHEMBL2321669 | 1.00 | PPARG (0.46) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL2341476 | 1.00 | PPARG (0.46) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL9016942 | 1.00 | PPARG (0.46) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL10872529 | 0.99 | PPARG (0.45) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL9390192 | 0.99 | PPARG (0.45) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL8966183 | 0.99 | AKR1B1 (0.44) | PPARGPPARDPPARAGPR84HDAC11 | |
| Stearic Acid SCHEMBL11745947 | 0.97 | PPARG (0.44) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL11744543 | 0.97 | PPARG (0.44) | PPARGPPARDPPARAGPR84HDAC11 | |
| Triaziquone SCHEMBL11745026 | 0.97 | PPARG (0.44) | PPARGPPARDPPARAGPR84HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110540679-B | Rubber composition for tire and pneumatic tire | 住友橡胶工业株式会社 | 2023-03-31 | — | — | CN | disclosed |
| CN-110540687-B | Rubber composition for tire and pneumatic tire | 住友橡胶工业株式会社 | 2023-03-10 | — | — | CN | disclosed |
| CN-111492000-B | Rubber composition and tire using same | 株式会社普利司通 | 2023-02-17 | — | — | CN | disclosed |
| CN-110730801-B | Sidewall reinforcing rubber for run flat tire and run flat tire | 株式会社普利司通 | 2022-07-19 | — | — | CN | disclosed |
| CN-114502629-A | Safety tyre | 株式会社普利司通 | 2022-05-13 | — | — | CN | disclosed |
| CN-114466888-A | Rubber composition and run-flat tire | 株式会社普利司通 | 2022-05-10 | — | — | CN | disclosed |
| CN-111032369-B | Pneumatic tire | 株式会社普利司通 | 2022-04-15 | — | — | CN | disclosed |
| CN-110382609-B | Studless tire | 住友橡胶工业株式会社 | 2022-03-22 | — | — | CN | disclosed |
| CN-110117365-B | Modified polymethylsiloxane, modified high-cis conjugated diene polymer, method for producing same, rubber composition, and tire | 奇美实业股份有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-109563183-B | Modified conjugated diene polymer, rubber composition thereof, and tire | 旭化成株式会社 | 2021-04-23 | — | — | CN | disclosed |
| WO-2017223536-A1 | DRUG COATED BALLOONS AND TECHNIQUES FOR INCREASING VASCULAR PERMEABILITY | ALSTON STEVEN M (US) | 2017-12-28 | — | — | WO | disclosed |
| US-20170367705-A1 | DRUG COATED BALLOONS AND TECHNIQUES FOR INCREASING VASCULAR PERMEABILITY | W. L. GORE & ASSOCIATES, INC. | 2017-12-28 | — | — | US | disclosed |
| US-9233191-B2 | Drug-coated medical devices | INNORA GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| EP-2793967-B1 | DRUG-COATED MEDICAL DEVICES | INNORA GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-20140322291-A1 | Drug-Coated Medical Devices | INNORA GMBH (DE) | 2014-10-30 | — | — | US | disclosed |
| EP-2793967-A1 | DRUG-COATED MEDICAL DEVICES | Innora GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013092416-A1 | DRUG-COATED MEDICAL DEVICES | INNORA GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-1165636-A4 | BISMUTH CARBOXYLATES AS CATALYSTS FOR CROSSLINKED BLOCKED ISOCYANATE WATERBONE COATINGS | KING INDUSTRIES INC (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1165636-A1 | BISMUTH CARBOXYLATES AS CATALYSTS FOR CROSSLINKED BLOCKED ISOCYANATE WATERBONE COATINGS | King Industries, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000047642-A1 | BISMUTH CARBOXYLATES AS CATALYSTS FOR CROSSLINKED BLOCKED ISOCYANATE WATERBONE COATINGS | KING INDUSTRIES, INC. (US) | 2000-08-17 | — | — | WO | disclosed |