SCHEMBL6535746

SCHEMBL6535746

CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.47
▸ BACE1 P56817 2/20 0.44
▸ NPY1R P25929 1/20 0.42
▸ NPY2R P49146 1/20 0.42
▸ NPY4R P50391 1/20 0.42
▸ FNTA P49354 7/20 0.41
▸ FNTB P49356 7/20 0.41
▸ PGGT1B P53609 4/20 0.41
▸ ERAP2 Q6P179 1/20 0.41
▸ ERAP1 Q9NZ08 1/20 0.41
▸ LNPEP Q9UIQ6 1/20 0.41
▸ LMNA P02545 1/20 0.40
▸ MMP7 P09237 1/20 0.40
▸ CPB2 Q96IY4 1/20 0.39
▸ CTSD P07339 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535743 1.00 FOLH1 (0.47) FOLH1BACE1NPY1RNPY2RNPY4R
SCHEMBL31343299 0.98 FOLH1 (0.48) FOLH1BACE1NPY1RNPY2RNPY4R
SCHEMBL7646961 0.96 FOLH1 (0.51) FOLH1NPY1RNPY2RNPY4RFNTA
SCHEMBL7646973 0.96 FOLH1 (0.51) FOLH1NPY1RNPY2RNPY4RFNTA
SCHEMBL8022959 0.93 FNTA (0.46) FOLH1FNTAFNTBPGGT1BLMNA
SCHEMBL30753797 0.91 FOLH1 (0.50) FOLH1BACE1NPY1RNPY2RNPY4R
SCHEMBL30400254 0.91 FOLH1 (0.54) FOLH1NPY1RNPY2RNPY4RFNTA
SCHEMBL30558190 0.91 NPY4R (0.48) FOLH1NPY1RNPY2RNPY4RERAP2
SCHEMBL18378078 0.91 NPY4R (0.48) FOLH1NPY1RNPY2RNPY4RERAP2
SCHEMBL18378081 0.91 NPY4R (0.48) FOLH1NPY1RNPY2RNPY4RERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015482-A4 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE UNIV TENNESSEE RES CORP (US) 2004-09-15 — — EP disclosed
US-6441134-B1 OLIGOPEPTIDE MEMBRANE TRANSPORTER WHICH IS NOT A MEMBER OF THE PEPTIDE TRANSPORT (PTR) OR ATP BINDING CASSETTE (ABC) FAMILIES; USE TARGETING ANTICANDIDAL (FUNGICIDAL) DRUGS THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2002-08-27 — — US disclosed
EP-1015482-A1 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2000-07-05 — — EP disclosed
WO-1998034950-A1 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 1998-08-13 — — WO disclosed
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