Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.52 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.52 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.52 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538190 | 0.89 | KDR (0.67) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537872 | 0.86 | KDR (0.57) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6538118 | 0.85 | KDR (0.56) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537795 | 0.85 | NPC1 (0.70) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537930 | 0.83 | KDR (0.54) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537536 | 0.82 | KDR (0.52) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537726 | 0.82 | TDP1 (0.61) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6538099 | 0.82 | CLK1 (0.55) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537710 | 0.82 | KDR (0.53) | L3MBTL1MEN1KMT2AKDRTDP1 | |
| SCHEMBL6537714 | 0.82 | KMT2A (0.61) | MEN1KMT2AKDRKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |