SCHEMBL6537374

SCHEMBL6537374

CC=C=CN1CCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.40
BRD2 P25440 1/20 0.40
CHRM2 P08172 4/20 0.34
CHRM5 P08912 4/20 0.34
CHRM1 P11229 4/20 0.34
CHRM3 P20309 4/20 0.34
CHRM4 P08173 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PIK3CD O00329 1/20 0.33
LMNA P02545 3/20 0.32
ALDH1A1 P00352 2/20 0.32
APEX1 P27695 2/20 0.32
PMP22 Q01453 2/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11031774 0.78 CHRM2 (0.33) BRD4BRD2CHRM2CHRM5CHRM1
SCHEMBL27443050 0.77
SCHEMBL649628 0.76
SCHEMBL14692624 0.75
SCHEMBL11825737 0.74 BRD4 (0.31) BRD4BRD2CHRM2CHRM5CHRM1
SCHEMBL195054 0.72
SCHEMBL19448367 0.72
SCHEMBL11827149 0.72
Propene SCHEMBL28161947 0.71 BRD4 (0.43) BRD4BRD2CHRM2CHRM5CHRM1
SCHEMBL1435579 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6806334-B2 PHARMACEUTICAL TABLET EXHIBITING RAPID DISSOLUTION AND DISINTEGRATION; MOISTURE RESISTANCE ISP INVESTMENTS INC. 2004-10-19 US claimed
US-20040054066-A1 Proliferous copolymer of vinyl pyrrolidone and vinyl acetate ISP INVESTMENTS INC. 2004-03-18 US claimed
US-6620900-B2 Excipient tablet with slow dissolution and disintegration ISP INVESTMENTS INC. 2003-09-16 US claimed
WO-2003066691-A1 PROLIFEROUS COPOLYMER OF VINYL PYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. (US) 2003-08-14 WO claimed
US-20030153705-A1 PROLIFEROUS COPOLYMER OF VINYL PYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. 2003-08-14 US claimed
EP-3377549-B1 PROLIFEROUS POLYMERS COMPRISING LACTAMIC MOIETIES ISP INVESTMENTS LLC (US) 2024-09-04 EP disclosed
CN-115354038-A Carbonic anhydrase immobilization method based on visible light induced graft polymerization 陕西科技大学 2022-11-18 CN disclosed
CN-113120880-A Preparation method of polymer carbon dots, polymer carbon dot film, preparation method and application TCL集团股份有限公司 2021-07-16 CN disclosed
US-10844154-B2 Proliferous copolymers comprising lactamic moieties ISP INVESTMENTS LLC (US) 2020-11-24 US disclosed
US-20180340034-A1 PROLIFEROUS COPOLYMERS COMPRISING LACTAMIC MOIETIES ISP INVESTMENTS LLC (US) 2018-11-29 US disclosed
EP-3377549-A1 PROLIFEROUS POLYMERS COMPRISING LACTAMIC MOIETIES ISP Investments LLC (US) 2018-09-26 EP disclosed
CN-102858845-A Hydrogel precursor formulation and production process thereof QGEL SA 2013-01-02 CN disclosed
US-6806334-B2 PHARMACEUTICAL TABLET EXHIBITING RAPID DISSOLUTION AND DISINTEGRATION; MOISTURE RESISTANCE ISP INVESTMENTS INC. 2004-10-19 US disclosed
US-20040054066-A1 Proliferous copolymer of vinyl pyrrolidone and vinyl acetate ISP INVESTMENTS INC. 2004-03-18 US disclosed
US-6620900-B2 Excipient tablet with slow dissolution and disintegration ISP INVESTMENTS INC. 2003-09-16 US disclosed
WO-2003066691-A1 PROLIFEROUS COPOLYMER OF VINYL PYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. (US) 2003-08-14 WO disclosed
US-20030153705-A1 PROLIFEROUS COPOLYMER OF VINYL PYRROLIDONE AND VINYL ACETATE ISP INVESTMENTS INC. 2003-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844154-B2 Proliferous copolymers comprising lactamic moieties PCNA, MKI67, CCNA1 BRD4 1116/4885BRD2 1918/4885CHRM2 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.