SCHEMBL6537388

SCHEMBL6537388

C/C=C/COP(=O)(OC/C=C/C)OC/C=C/C

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537391 1.00 TSHR (0.41) TSHRCYP3A4ALDH1A1
SCHEMBL25291824 0.91 TSHR (0.59) TSHRCYP3A4
SCHEMBL2594778 0.90 TSHR (0.32) TSHR
SCHEMBL19348635 0.85
SCHEMBL19348722 0.85
SCHEMBL19348735 0.85
SCHEMBL19348604 0.85
SCHEMBL1506680 0.79
SCHEMBL19348636 0.79
SCHEMBL13268920 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013130481-A1 RECOMBINANT HOST CELLS AND PROCESSES FOR PRODUCING 1,3-BUTADIENE THROUGH A CROTONOL INTERMEDIATE CODEXIS, INC. (US) 2013-09-06 WO claimed
US-6765049-B2 POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS, CLAY IS PARTIALLY EXFOLIATED WITHIN AND SURFACTANTS; THICKENERS, DISPERSANTS, PLASTICS ADDITIVES, ADHESIVES, COATINGS, FLEXOGRAPHIC INKS, OVERPRINT VARNISHES, AND DRY CEMENT POWDER ROHM AND HAAS COMPANY 2004-07-20 US claimed
EP-1325037-A2 HIGH ACID AQUEOUS NANOCOMPOSITE DISPERSIONS ROHM AND HAAS COMPANY (US) 2003-07-09 EP claimed
US-20020055580-A1 High acid aqueous nanocomposite dispersions ROHM AND HAAS COMPANY 2002-05-09 US claimed
WO-2002024757-A2 HIGH ACID AQUEOUS NANOCOMPOSITE DISPERSIONS ROHM AND HAAS COMPANY (US) 2002-03-28 WO claimed
EP-0348565-B1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM & HAAS (US) 1995-03-22 EP claimed
US-5266646-A Thickeners for waterbase paints; viscosity stabilizers to colorants; heat resistance; blister resistance; color float; syneresis resistance ROHM AND HAAS COMPANY (US) 1993-11-30 US claimed
US-5212251-A Sequential emulsion polymerization of unsaturated compounds having acid-ionizable functionality to make core acid insoluble and shell acid soluble; protective coatings; inks; clear overprint varnishes; paper and fiber treatment ROHM AND HAAS COMPANY (US) 1993-05-18 US claimed
EP-0277874-B1 COMPOSITE COPOLYMER, ITS PREPARATION PROCESS AND ITS USE IN THE REINFORCEMENT OF RIGID THERMOPLASTIC MATRICES ELF ATOCHEM S.A. (FR) 1993-04-28 EP claimed
EP-0348565-A1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM AND HAAS COMPANY (US) 1990-01-03 EP claimed
US-4876313-A FOR INKS, COATINGS, VARNISHES,CEMENTS, LEATHER; ACRYLIC ACIDS, ANHYDRIDES AND OTHER UNSATURATED MONOMERS ROHM AND HAAS COMPANY 1989-10-24 US claimed
CN-112877370-A Modified microorganism and method for producing butadiene using the same 布拉斯科南美公司 2021-06-01 CN disclosed
EP-2791342-B1 MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME BRASKEM SA (BR) 2020-04-29 EP disclosed
US-20190218578-A1 MICROBIAL ORGANISMS FOR CONVERTING ACETYL-COA INTO CROTYL ALCOHOL AND METHODS FOR PRODUCING CROTYL ALCOHOL WHITE DOG LABS, INC. (US) 2019-07-18 US disclosed
US-10273505-B2 Modified microorganisms and methods of making butadiene using same BRASKEM S.A. (BR) 2019-04-30 US disclosed
EP-0473972-A1 Multicomponent-elastomers based on polyurethane ureas and crosslinked finely divided rubber polymers and process for their preparation BAYER AG (DE) 1992-03-11 EP disclosed
EP-0444791-A1 Polymeric thickeners for aqueous-based coatings ROHM AND HAAS COMPANY (US) 1991-09-04 EP disclosed
EP-0398576-A2 Multi-stage polymer particle having a hydrophobically-modified ionically soluble stage ROHM AND HAAS COMPANY (US) 1990-11-22 EP disclosed
EP-0348565-A1 Polymers comprising alkali-insoluble core/alkali-soluble shell and compositions thereof ROHM AND HAAS COMPANY (US) 1990-01-03 EP disclosed
US-4876313-A FOR INKS, COATINGS, VARNISHES,CEMENTS, LEATHER; ACRYLIC ACIDS, ANHYDRIDES AND OTHER UNSATURATED MONOMERS ROHM AND HAAS COMPANY 1989-10-24 US disclosed