Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537838 | 0.89 | MAPT (0.46) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6537969 | 0.89 | KMT2A (0.39) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6537846 | 0.85 | MAPT (0.43) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6538315 | 0.84 | MAPT (0.45) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6537686 | 0.84 | MAPT (0.45) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6538068 | 0.84 | MAPT (0.45) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6538090 | 0.83 | TP53 (0.44) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6537564 | 0.83 | MEN1 (0.48) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6538112 | 0.82 | MAPT (0.43) | KMT2AMEN1MAPTSMN1; SMN2POLB | |
| SCHEMBL6538105 | 0.82 | MAPT (0.45) | KMT2AMEN1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |