Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537631 | 0.89 | POLB (0.53) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6537633 | 0.88 | POLB (0.52) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6538156 | 0.87 | POLB (0.51) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL6537756 | 0.86 | POLB (0.50) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL6537917 | 0.83 | POLB (0.47) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6537873 | 0.83 | JAK2 (0.42) | KMT2ASMN1; SMN2 | |
| SCHEMBL6537402 | 0.80 | JAK2 (0.43) | KMT2ASMN1; SMN2 | |
| SCHEMBL6538082 | 0.80 | JAK2 (0.43) | KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7831807 | 0.78 | POLB (0.53) | POLBRAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6537791 | 0.78 | JAK2 (0.41) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |