Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 1.00 |
| ▸ | HDAC4 | P56524 | 2/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 2/20 | 1.00 |
| ▸ | HDAC2 | Q92769 | 2/20 | 1.00 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 1.00 |
| ▸ | TNKS | O95271 | 1/20 | 1.00 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 1.00 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 1.00 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 1.00 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 1.00 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 1.00 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.73 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamic Acid SCHEMBL1332 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL50466 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL29989544 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL653827 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL3406486 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1333 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL1706935 | 1.00 | HCAR2 (1.00) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL579400 | 0.97 | HCAR2 (0.95) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL6444122 | 0.97 | HDAC3 (0.95) | HCAR2HDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL2816036 | 0.97 | HCAR2 (0.95) | HCAR2HDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925323-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. Hoffmann-La Roche AG (CH) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014083026-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-05 | — | — | WO | disclosed |
| US-8119804-B2 | Organic semiconducting layers | MERCK PATENT GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| CN-1784457-B | Imide-linked maleimide and polymaleimide compounds | ADVANCED APPLIED ADHESIVES | 2010-07-14 | — | — | CN | disclosed |
| CN-101223181-A | Adhesive compositions containing cyclosiloxane | DESIGNER MOLECULES INC (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-1784457-A | Imide-linked maleimide and polymaleimide compounds | ADVANCED APPLIED ADHESIVES (US) | 2006-06-07 | — | — | CN | disclosed |