Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.86 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.86 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6539537 | 0.93 | ADRB3 (0.81) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL6538626 | 0.93 | ADRB3 (1.00) | ADRB3ADRB1ADRB2ALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL6538594 | 0.92 | ADRB3 (0.98) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6538774 | 0.91 | ADRB3 (0.88) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6538752 | 0.91 | ADRB3 (0.83) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL6538556 | 0.90 | ADRB3 (0.86) | ADRB3ADRB1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6538900 | 0.87 | ADRB3 (0.78) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL6539731 | 0.87 | ADRB3 (1.00) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| SCHEMBL7531125 | 0.86 | ADRB3 (0.86) | ADRB3ADRB1ADRB2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6539367 | 0.85 | ADRB3 (0.92) | ADRB3ADRB1ADRB2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |