Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538626 | 0.90 | ADRB3 (1.00) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL6538997 | 0.89 | ADRB3 (0.82) | ADRB3ADRB1MAPTADRB2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6538594 | 0.89 | ADRB3 (0.98) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL6538446 | 0.88 | ADRB3 (0.80) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL6539933 | 0.85 | ADRB3 (0.85) | ADRB3ADRB1MAPTADRB2CYP2D6 | |
| SCHEMBL7531125 | 0.85 | ADRB3 (0.86) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL7692859 | 0.85 | ADRB3 (0.79) | ADRB3ADRB1MAPTADRB2CYP2D6 | |
| SCHEMBL6538702 | 0.85 | ADRB3 (0.74) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6538774 | 0.84 | ADRB3 (0.88) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7041978 | 0.84 | ADRB3 (0.74) | ADRB3ADRB1ADRB2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |