Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539307 | 1.00 | ADRB3 (1.00) | ADRB3ADRB1BACE1ADRB2SLC2A1 | |
| SCHEMBL6539840 | 0.90 | ADRB3 (0.81) | ADRB3ADRB1BACE1ADRB2SLC2A1 | |
| SCHEMBL6539834 | 0.90 | ADRB3 (0.81) | ADRB3ADRB1BACE1ADRB2SLC2A1 | |
| SCHEMBL6539557 | 0.85 | ADRB3 (0.74) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL6539553 | 0.82 | ADRB3 (0.69) | ADRB3ADRB1BACE1ADRB2SLC2A1 | |
| SCHEMBL7692035 | 0.82 | ADRB3 (0.69) | ADRB3ADRB1ADRB2SLC2A1ADRA1D | |
| SCHEMBL7692032 | 0.82 | ADRB3 (0.69) | ADRB3ADRB1ADRB2SLC2A1ADRA1D | |
| Hydrochloric Acid SCHEMBL6538854 | 0.81 | ADRB3 (0.68) | ADRB3ADRB1ADRB2SLC2A1ADRA1D | |
| Hydrochloric Acid SCHEMBL6538857 | 0.81 | ADRB3 (0.68) | ADRB3ADRB1ADRB2SLC2A1ADRA1D | |
| SCHEMBL6540039 | 0.81 | ADRB3 (0.67) | ADRB3ADRB1ADRB2SLC2A1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |