Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.80 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6539492 | 0.96 | ADRB3 (0.73) | ADRB3ADRB1MAPTNAMPTADRB2 | |
| SCHEMBL6538836 | 0.93 | ADRB3 (0.81) | ADRB3ADRB1MAPTNPC1RAB9A | |
| SCHEMBL6538626 | 0.89 | ADRB3 (1.00) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL7531125 | 0.89 | ADRB3 (0.86) | ADRB3ADRB1MAPTADRB2NPC1 | |
| Hydrochloric Acid SCHEMBL6538594 | 0.88 | ADRB3 (0.98) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL6539711 | 0.87 | ADRB3 (0.83) | ADRB3ADRB1MAPTADRB2 | |
| Trifluoroacetic Acid SCHEMBL6538740 | 0.87 | ADRB3 (0.68) | ADRB3ADRB1MAPT | |
| SCHEMBL6539933 | 0.87 | ADRB3 (0.85) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL7532101 | 0.85 | ADRB3 (1.00) | ADRB3ADRB1MAPTADRB2 | |
| SCHEMBL6538957 | 0.85 | ADRB3 (0.73) | ADRB3ADRB1MAPTADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6826033-B2 | BETA 3 ADRENERGIC RECEPTOR AGONISTS; TREATMENT OF POLLAKIURIA, URINARY INCONTINENCE, OBESITY OR DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |