Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.76 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6538830 | 0.91 | ADRB3 (0.76) | ADRB3ADRB1NPC1RAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL6539537 | 0.91 | ADRB3 (0.81) | ADRB3ADRB1MAPT | |
| Trifluoroacetic Acid SCHEMBL6539409 | 0.90 | ADRB3 (0.75) | ADRB3ADRB1NPC1RAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL6539886 | 0.90 | ADRB3 (0.75) | ADRB3ADRB1NPC1RAB9AMAPT | |
| Trifluoroacetic Acid SCHEMBL6539730 | 0.90 | ADRB3 (0.75) | ADRB3ADRB1MAPT | |
| Trifluoroacetic Acid SCHEMBL6539502 | 0.88 | ADRB3 (0.80) | ADRB3ADRB1SMN1; SMN2MAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL6538460 | 0.88 | ADRB3 (0.71) | ADRB3ADRB1MAPT | |
| Trifluoroacetic Acid SCHEMBL6538892 | 0.88 | ADRB3 (0.79) | ADRB3ADRB1MAPT | |
| Trifluoroacetic Acid SCHEMBL6539368 | 0.88 | ADRB3 (0.70) | ADRB3ADRB1NPC1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6538789 | 0.88 | ADRB3 (0.70) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040037022-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| WO-2002024635-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-28 | — | — | WO | disclosed |