⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056291 | 1.00 | — | — | |
| SCHEMBL13591172 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL21056277 | 1.00 | GABRR1 (0.50) | — | |
| SCHEMBL6787830 | 0.85 | SLC1A3 (0.39) | — | |
| SCHEMBL6789915 | 0.85 | SLC1A3 (0.39) | — | |
| SCHEMBL6539858 | 0.80 | — | — | |
| SCHEMBL6789204 | 0.80 | HDAC2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL28754350 | 0.80 | — | — | |
| SCHEMBL21649465 | 0.79 | GABRR1 (0.38) | — | |
| SCHEMBL21649466 | 0.79 | GABRR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11608332-B2 | FGFR4 inhibitor and preparation method and use thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-03-21 | — | — | US | disclosed |
| CN-109563091-B | FGFR4 inhibitor and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20220024913-A1 | FGFR4 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-01-27 | — | — | US | disclosed |
| EP-3498707-A1 | FGFR4 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |
| US-6733985-B1 | FOR MONITORING EXTRINSIC BLOOD COAGULATION ACTIVITIES; PREPARED FROM RECOMBINANT TISSUE FACTOR AND SYNTHETIC PHOSPHOLIPIDS | INTERNATIONAL TECHNIDYNE CORPORATION | 2004-05-11 | — | — | US | disclosed |