Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541826 | 0.90 | CXCR4 (0.55) | BCHEACHECHRM2CHRM4CHRM5 | |
| SCHEMBL23459312 | 0.83 | KMT2A (0.49) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6540368 | 0.78 | TACR1 (0.46) | CHRM5CXCR4KMT2ATSHRSIGMAR1 | |
| SCHEMBL23459007 | 0.73 | SMN1; SMN2 (0.46) | KMT2ASIGMAR1MEN1CYP2D6 | |
| SCHEMBL23459009 | 0.73 | SMN1; SMN2 (0.46) | KMT2ASIGMAR1MEN1CYP2D6 | |
| SCHEMBL3210838 | 0.71 | CHRM2 (0.63) | BCHEACHECHRM2CHRM4CHRM5 | |
| SCHEMBL6333454 | 0.71 | CXCR4 (0.48) | BCHEACHECHRM2CXCR4DPP7 | |
| SCHEMBL23023124 | 0.71 | CHRM2 (0.59) | BCHEACHECHRM2CHRM4CHRM5 | |
| SCHEMBL4918396 | 0.70 | CHRM2 (0.79) | BCHEACHECHRM2CHRM4CHRM5 | |
| SCHEMBL29997324 | 0.70 | CYP2D6 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787543-B2 | PREPARATION OF TACHYKININ ANTAGONISTS; SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |