SCHEMBL6542263

SCHEMBL6542263

CC(N)SCC(N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.50
KIF11 P52732 5/20 0.47
SLC1A3 P43003 4/20 0.45
SLC1A2 P43004 4/20 0.45
SLC1A1 P43005 3/20 0.45
ARG1 P05089 1/20 0.44
ARG2 P78540 1/20 0.44
NOS2 P35228 3/20 0.43
NOS1 P29475 2/20 0.43
NOS3 P29474 1/20 0.43
BHMT Q93088 2/20 0.42
BHMT2 Q9H2M3 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC7A11 Q9UPY5 1/20 0.42
ALDH1A1 P00352 1/20 0.40
ALOX15 P16050 1/20 0.40
GRIK1 P39086 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA4 P48058 1/20 0.39
GRIK3 Q13003 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6542267 1.00 SLC7A5 (0.50) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL9463162 0.98 SLC7A5 (0.48) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
Hydrochloric Acid SCHEMBL9462892 0.98 SLC7A5 (0.48) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL28948326 0.86 SLC7A5 (0.50) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL13902860 0.86 SLC7A5 (0.50) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL13988062 0.86 SLC7A5 (0.50) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL6231968 0.84 SLC7A5 (0.48) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL3715550 0.84 SLC7A5 (0.48) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL15600074 0.82 SLC7A5 (0.46) SLC7A5KIF11SLC1A3SLC1A2SLC1A1
SCHEMBL8518857 0.82 SLC7A5 (0.46) SLC7A5KIF11SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040043953-A1 Genes of corynebacterium BASF SE (DE) 2004-03-04 US disclosed
EP-1345714-A1 GENES OF CORYNEBACTERIUM BASF AKTIENGESELLSCHAFT (DE) 2003-09-24 EP disclosed
EP-1261718-A2 CORYNEBACTERIUM GLUTAMICUM GENES ENCODING METABOLIC PATHWAY PROTEINS BASF AKTIENGESELLSCHAFT (DE) 2002-12-04 EP disclosed
WO-2002051231-A1 GENES OF CORYNEBACTERIUM BASF AKTIENGESELLSCHAFT (DE) 2002-07-04 WO disclosed
WO-2001066573-A2 CORYNEBACTERIUM GLUTAMICUM GENES ENCODING METABOLIC PATHWAY PROTEINS BASF AKTIENGESELLSCHAFT (US) 2001-09-13 WO disclosed
WO-1999024465-A9 STABILIZED PRIMATE LENTIVIRUS ENVELOPE GLYCOPROTEINS DANA FARBER CANCER INST INC (US) 1999-08-12 WO disclosed
WO-1999024465-A1 STABILIZED PRIMATE LENTIVIRUS ENVELOPE GLYCOPROTEINS DANA-FARBER CANCER INSTITUTE (US) 1999-05-20 WO disclosed
US-4594341-A Hypotensive agent MERCK & CO., INC. (US) 1986-06-10 US disclosed
EP-0068173-B1 PERHYDRO-1,4-THIAZEPIN-5-ONE AND PERHYDRO-1,4-THIAZOCIN-5-ONE DERIVATIVES, PROCESS FOR PREPARING AND PHARMCEUTICAL COMPOSITION CONTAINING THE SAME MERCK & CO. INC. (US) 1984-09-26 EP disclosed
EP-0068173-A1 Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same MERCK & CO. INC. (US) 1983-01-05 EP disclosed