Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11638039 | 0.95 | TSHR (0.39) | TSHRFNTAFNTBLMNAHSD17B10 | |
| SCHEMBL26135862 | 0.91 | TSHR (0.41) | TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL11285445 | 0.83 | TP53 (0.40) | TSHRHSD17B10MAPTKMT2ACYP3A4 | |
| SCHEMBL11640427 | 0.82 | TP53 (0.39) | TSHRLMNAHSD17B10MAPTALDH1A1 | |
| SCHEMBL7495347 | 0.81 | MME (0.39) | FNTAFNTBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL7495343 | 0.81 | MME (0.39) | FNTAFNTBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL21002272 | 0.79 | GRIN2D (0.31) | TSHRLMNA | |
| SCHEMBL21002274 | 0.79 | GRIN2D (0.31) | TSHRLMNA | |
| SCHEMBL10727487 | 0.78 | TSHR (0.35) | TSHRLMNAHSD17B10MAPTALDH1A1 | |
| SCHEMBL10727481 | 0.78 | TSHR (0.35) | TSHRLMNAHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730242-B2 | EFFICIENCY | THE UNIVERSITY OF ROCHESTER | 2004-05-04 | — | — | US | disclosed |
| US-20030164473-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| US-6558572-B2 | Optical device | UNIVERSITY OF ROCHESTER | 2003-05-06 | — | — | US | disclosed |
| US-20010036517-A1 | Glass-forming liquid crystalline compositions and optical devices formed therefrom | NATIONAL SCIENCE FOUNDATION | 2001-11-01 | — | — | US | disclosed |
| EP-0729498-B1 | CHIRAL NEMATIC LIQUID CRYSTALLINE COMPOSITIONS | UNIV ROCHESTER (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-0729498-A1 | CHIRAL NEMATIC LIQUID CRYSTALLINE COMPOSITIONS | THE UNIVERSITY OF ROCHESTER (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729498-A4 | CHIRAL NEMATIC LIQUID CRYSTALLINE COMPOSITIONS | UNIV ROCHESTER (US) | 1996-07-16 | — | — | EP | disclosed |
| US-5514296-A | Glassy low molar mass chiral nematic liquid crystalline compositions and optical articles formed therefrom | THE UNIVERSITY OF ROCHESTER (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1995014067-A1 | CHIRAL NEMATIC LIQUID CRYSTALLINE COMPOSITIONS | UNIVERSITY OF ROCHESTER (US) | 1995-05-26 | — | — | WO | disclosed |
| US-5378393-A | That produce reflected light in visible and infrared regions; thermotropic compounds that include a cycloaliphatic radical | THE UNIVERSITY OF ROCHESTER (US) | 1995-01-03 | — | — | US | disclosed |
| US-4959293-A | Deep UV photoresist with alkyl 2-diazo-1-ones as solubility modification agents | J. T. BAKER, INC. (US) | 1990-09-25 | — | — | US | disclosed |
| US-4291170-A | A,B-UNSATURATED ESTER, KETONE, PRIMARY AMINE OR SCHIFF BASE, ACID | STAMICARBON, B.V. (NL) | 1981-09-22 | — | — | US | disclosed |
| US-4128560-A | Tricyclic alkylamine derivatives | AYERST MCKENNA & HARRISON LTD. (CA) | 1978-12-05 | — | — | US | disclosed |
| US-4057559-A | ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |