Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 13/20 | 0.72 |
| ▸ | CA9 | Q16790 | 13/20 | 0.72 |
| ▸ | CA1 | P00915 | 11/20 | 0.72 |
| ▸ | CA6 | P23280 | 5/20 | 0.72 |
| ▸ | CA7 | P43166 | 5/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.72 |
| ▸ | CA4 | P22748 | 5/20 | 0.72 |
| ▸ | CA5A | P35218 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | CA3 | P07451 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802536 | 0.91 | CA12 (0.63) | CA12CA9CA1CA6CA7 | |
| SCHEMBL13376996 | 0.89 | CA12 (0.60) | CA12CA9CA1CA6CA7 | |
| SCHEMBL14802647 | 0.89 | GBA1 (0.65) | CA12CA9CA1CA6CA7 | |
| SCHEMBL14802648 | 0.85 | CA12 (0.59) | CA12CA9CA1CA6CA7 | |
| Herniarin SCHEMBL17629468 | 0.84 | CA12 (1.00) | CA12CA9CA1CA6CA7 | |
| SCHEMBL10813314 | 0.84 | CA12 (0.68) | CA12CA9CA1CA6CA7 | |
| Herniarin SCHEMBL61221 | 0.84 | CA12 (1.00) | CA12CA9CA1CA6CA7 | |
| SCHEMBL21133102 | 0.84 | CA12 (0.68) | CA12CA9CA1CA6CA7 | |
| SCHEMBL21251462 | 0.84 | CA12 (0.68) | CA12CA9CA1CA6CA7 | |
| Herniarin SCHEMBL29437733 | 0.84 | CA12 (1.00) | CA12CA9CA1CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750032-B2 | DETECTION OF BLOOD COAGULATION DEFECTS; OBTAIN BLOOD SAMPLE, INCUBATE WITH MODULATOR, MONITOR COAGULATION AND DISSOLUTION, EVALUATE FOR DEFECTS | DADE BEHRING MARBURG GMBH (DE) | 2004-06-15 | — | — | US | claimed |
| US-20030027235-A1 | Novel method and diagnostic agent for hemostasis diagnosis | DADE BEHRING MARBURG GMBH (DE) | 2003-02-06 | — | — | US | claimed |
| US-6187594-B1 | MIXING SAMPLE AND AT LEAST TWO SUBSTANCES WHICH INTERACT WITH EACH OTHER, AT LEAST ONE SUBSTANCE BINDS TO THE BLOOD CLOT; MEASURING SIGNAL; CORRELATING WITH DEGREE OF PLATELET AGGREGATION, CLOT FORMATION AND/OR CLOT DISSOLUTION | DADE BEHRING MARBURG GMBH (DE) | 2001-02-13 | — | — | US | claimed |
| US-6800768-B1 | STABLE PHOTOACTIVE COUMARIN COMPOUNDS THAT CAN BE USED AS PHOTO-CROSSLINKING REAGENTS IN NUCLEIC ACID HYBRIDIZATION ASSAYS AND THERAPEUTIC APPLICATIONS | NAXCOR, INC. | 2004-10-05 | — | — | US | disclosed |
| US-6750032-B2 | DETECTION OF BLOOD COAGULATION DEFECTS; OBTAIN BLOOD SAMPLE, INCUBATE WITH MODULATOR, MONITOR COAGULATION AND DISSOLUTION, EVALUATE FOR DEFECTS | DADE BEHRING MARBURG GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| WO-2004022703-A2 | NON-NUCLEOSIDIC COUMARIN DERIVATIVES AS POLYNUCLEOTIDE-CROSSLINKING AGENTS | NAXCOR, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| US-6632599-B1 | Detection and determination of solid phase-associated factors | DADE BEHRING MARBURG GMBH (DE) | 2003-10-14 | — | — | US | disclosed |
| US-20030027235-A1 | Novel method and diagnostic agent for hemostasis diagnosis | DADE BEHRING MARBURG GMBH (DE) | 2003-02-06 | — | — | US | disclosed |
| US-6482653-B1 | Method and diagnostic agent for hemostasis diagnosis | DADE BEHRING MARBURG GMBH (DE) | 2002-11-19 | — | — | US | disclosed |
| US-6187594-B1 | MIXING SAMPLE AND AT LEAST TWO SUBSTANCES WHICH INTERACT WITH EACH OTHER, AT LEAST ONE SUBSTANCE BINDS TO THE BLOOD CLOT; MEASURING SIGNAL; CORRELATING WITH DEGREE OF PLATELET AGGREGATION, CLOT FORMATION AND/OR CLOT DISSOLUTION | DADE BEHRING MARBURG GMBH (DE) | 2001-02-13 | — | — | US | disclosed |