Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.81 |
| ▸ | ACHE | P22303 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92055 | 0.90 | TSHR (1.00) | TSHRACHELMNAKMT2AGAA | |
| SCHEMBL31183022 | 0.90 | TSHR (1.00) | TSHRACHELMNAKMT2AGAA | |
| SCHEMBL2486973 | 0.90 | TSHR (1.00) | TSHRACHELMNAKMT2AGAA | |
| Bromide SCHEMBL27319679 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| SCHEMBL32667964 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| Methane SCHEMBL27860742 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| SCHEMBL9734443 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| SCHEMBL9734192 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| Hydrochloric Acid SCHEMBL11149191 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA | |
| Ammonia Solution, Strong SCHEMBL27653572 | 0.88 | TSHR (0.96) | TSHRACHELMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-109516987-A | A kind of AVM hereinafter Batan centre preparation | 江西富祥药业股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-107805212-A | A kind of preparation method of the aminobenzene sulfonamide of 2 methyl 5 | 宿迁德威化工有限公司 | 2018-03-16 | — | — | CN | disclosed |
| CN-103492028-B | Sulfonaminoquinoline hepcidin antagonists | 维福（国际）股份公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-104829542-A | Aniline pyrimidine compound, preparation method and medicinal application thereof | SHANGHAI INST MATERIA MEDICA | 2015-08-12 | — | — | CN | disclosed |
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |
| CN-102791709-A | Arylsulfonamide pyridine-pyridinone derivatives, preparation of same, and therapeutic use thereof | SANOFI AVENTIS | 2012-11-21 | — | — | CN | disclosed |
| CN-100351243-C | Peptide nucleic acid oligomers from 1-benzenesulfonyl-3-amino acid side chain-4- (2-nucleobase acetyl) -piperazin-2-one | PANAGENE INC (KR) | 2007-11-28 | — | — | CN | disclosed |
| CN-1749244-A | Refining method of aromatic benzene sulfonyl chloride | KANGAITE WEIXUN PENGLAI CHEMIS (CN) | 2006-03-22 | — | — | CN | disclosed |
| CN-1745087-A | Novel tricyclic azepine derivatives, method for production therof and pharmaceutical compositions comprising the same | SERVIER LAB (FR) | 2006-03-08 | — | — | CN | disclosed |
| CN-1642923-A | Peptide nucleic acid oligomers from 1-benzenesulfonyl-3-amino acid side chain-4-(2-nucleobase(acetyl))-piperazin-2-ones | PANAGENE INC (KR) | 2005-07-20 | — | — | CN | disclosed |
| US-20040266766-A1 | Selective urokinase inhibitors | WILEX AG (DE) | 2004-12-30 | — | — | US | disclosed |
| CN-1037568-C | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1998-03-04 | — | — | CN | disclosed |
| CN-1165143-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1165144-A | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-11-19 | — | — | CN | disclosed |
| CN-1066266-A | PHOSPHOSULFONATE HERBICIDES | ROHM & HAAS (US) | 1992-11-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266766-A1 | Selective urokinase inhibitors | PLAU, PLAUR, SERPINE1 | TSHR 2812/4885ACHE 3446/4885LMNA 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.