SCHEMBL6543166

SCHEMBL6543166

CCCCN(CCc1ccc(OC(C)(C)C(=O)O)cc1)c1nc2ccccc2o1

nearest known ligand 0.93

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.93
PPARA Q07869 16/20 0.93
PPARD Q03181 8/20 0.93
ELANE P08246 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6543339 0.97 PPARG (0.98) PPARGPPARAPPARD
SCHEMBL6542972 0.96 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL6542967 0.96 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL6543008 0.96 PPARG (1.00) PPARGPPARAPPARD
SCHEMBL6544137 0.96 PPARG (0.86) PPARGPPARAPPARDELANE
SCHEMBL6544078 0.95 PPARG (0.88) PPARGPPARAPPARD
SCHEMBL6543064 0.93 PPARG (0.91) PPARGPPARAPPARD
SCHEMBL6544131 0.93 PPARG (0.84) PPARGPPARAPPARD
SCHEMBL6543033 0.93 PPARG (0.84) PPARGPPARAPPARD
SCHEMBL6544130 0.93 PPARG (0.93) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1433786-A1 Benzoxazole compound and pharmaceutical composition containing the compound Kowa Company Ltd. (JP) 2004-06-30 EP disclosed
US-6653334-B1 Electively activate peroxisome proliferator activated receptors KOWA CO., LTD. (JP) 2003-11-25 US disclosed