Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.84 |
| ▸ | PPARG | P37231 | 17/20 | 0.84 |
| ▸ | PPARD | Q03181 | 12/20 | 0.84 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543456 | 1.00 | PPARA (0.84) | PPARAPPARGPPARDCXCR4CMKLR1 | |
| SCHEMBL6543468 | 1.00 | PPARA (0.84) | PPARAPPARGPPARDCXCR4CMKLR1 | |
| SCHEMBL6544258 | 0.99 | PPARA (0.83) | PPARAPPARGPPARDCXCR4CMKLR1 | |
| SCHEMBL6544018 | 0.96 | PPARA (0.78) | PPARAPPARGPPARDCXCR4CMKLR1 | |
| SCHEMBL6544126 | 0.93 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL6542962 | 0.92 | PPARG (0.93) | PPARAPPARGPPARD | |
| SCHEMBL6544130 | 0.92 | PPARG (0.93) | PPARAPPARGPPARD | |
| SCHEMBL6542967 | 0.92 | PPARG (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6542972 | 0.92 | PPARG (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6543008 | 0.92 | PPARG (1.00) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |