Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.64 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730529 | 0.99 | F2R (0.64) | F2RTHRATHRBMAPTKDM4E | |
| Bromide SCHEMBL1729491 | 0.91 | F2R (0.61) | F2RTHRATHRBMAPTKDM4E | |
| Bromide SCHEMBL1730629 | 0.91 | F2R (0.61) | F2RTHRATHRBMAPTKDM4E | |
| Bromide SCHEMBL1732147 | 0.90 | F2R (0.62) | F2RMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL14468847 | 0.90 | F2R (0.52) | F2RTHRATHRBMAPTKDM4E | |
| SCHEMBL1729286 | 0.90 | F2R (0.65) | F2RMAPTKDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL5482408 | 0.89 | F2R (0.65) | F2RTHRATHRBMAPTKDM4E | |
| Bromide SCHEMBL1730193 | 0.89 | F2R (0.66) | F2RMAPTKDM4ERAB9ANPC1 | |
| Bromide SCHEMBL1731057 | 0.89 | F2R (0.62) | F2RTHRATHRBMAPTKDM4E | |
| Bromide SCHEMBL1729476 | 0.89 | F2R (0.62) | F2RTHRATHRBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |