Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487370 | 0.85 | PPARG (0.60) | PPARG | |
| SCHEMBL3486572 | 0.84 | PPARG (0.61) | PPARGESRRA | |
| SCHEMBL3488145 | 0.84 | PPARG (0.61) | PPARGESRRA | |
| SCHEMBL3487158 | 0.82 | PPARG (0.66) | PPARG | |
| SCHEMBL3487083 | 0.82 | PPARG (0.62) | PPARGESRRA | |
| SCHEMBL3487226 | 0.82 | PPARG (0.62) | PPARG | |
| SCHEMBL3487449 | 0.81 | PPARG (0.59) | PPARGESRRA | |
| SCHEMBL3487134 | 0.81 | PPARG (0.59) | PPARGESRRA | |
| SCHEMBL3486865 | 0.81 | PPARG (0.63) | PPARGESRRA | |
| SCHEMBL3488585 | 0.81 | PPARG (0.63) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022272-B1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | SANKYO CO (JP) | 2004-05-26 | — | — | EP | disclosed |
| US-6432993-B1 | BENZIMIDAZOLE OR IMIDAZO(4,5-B)PYRIDINE DERIVATES; IMMUNOMODULATORS; ALDOSE REDUCTASE AND LIPOXYGENASE INHIBITORS; DIABETES; PREVENTS LIPID PEROXIDATION; ANTILIPEMIC, HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 2002-08-13 | — | — | US | disclosed |
| EP-1022272-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS | Sankyo Company Limited (JP) | 2000-07-26 | — | — | EP | disclosed |