Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5488710 | 0.88 | F2R (0.41) | F2R | |
| Bromide SCHEMBL1732004 | 0.81 | F2R (0.41) | F2R | |
| Bromide SCHEMBL1730612 | 0.79 | F2R (0.39) | F2R | |
| Bromide SCHEMBL1730527 | 0.71 | F2R (0.44) | F2R | |
| Bromide SCHEMBL1732015 | 0.71 | F2R (0.47) | F2R | |
| Bromide SCHEMBL1731757 | 0.70 | F2R (0.39) | F2R | |
| Bromide SCHEMBL1731184 | 0.69 | F2R (0.40) | F2R | |
| Bromide SCHEMBL1732226 | 0.69 | F2R (0.39) | F2R | |
| Bromide SCHEMBL1731729 | 0.69 | F2R (0.42) | F2R | |
| Bromide SCHEMBL5487341 | 0.69 | F2R (0.40) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |