Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1731009 | 0.89 | F2R (0.40) | F2RMAPTLMNA | |
| SCHEMBL1732187 | 0.85 | F2R (0.36) | F2R | |
| Bromide SCHEMBL1730884 | 0.85 | F2R (0.37) | F2RMAPTLMNAKDM4ENPC1 | |
| SCHEMBL6544035 | 0.84 | F2R (0.37) | F2RMAPTKDM4ENPC1RAB9A | |
| SCHEMBL14449076 | 0.83 | F2R (0.44) | F2R | |
| Hydrochloric Acid SCHEMBL1730414 | 0.83 | F2R (0.44) | F2R | |
| Hydrochloric Acid SCHEMBL1731567 | 0.82 | F2R (0.42) | F2RMAPTLMNAKDM4ENPC1 | |
| Bromide SCHEMBL1731332 | 0.82 | F2R (0.40) | F2RMAPTLMNAKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL5481374 | 0.82 | F2R (0.39) | F2RMAPTLMNA | |
| SCHEMBL14449150 | 0.81 | F2R (0.39) | F2RMAPTLMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |