Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436404 | 1.00 | MEN1 (0.45) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6525043 | 1.00 | MEN1 (0.45) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6545478 | 1.00 | MEN1 (0.45) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11439282 | 0.96 | HSD17B10 (0.46) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL1575700 | 0.89 | TSHR (0.57) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL212883 | 0.89 | TSHR (0.57) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL11436017 | 0.89 | TSHR (0.57) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL6544683 | 0.89 | TSHR (0.57) | MEN1KMT2AHTTTHRBMAPT | |
| Propylene Glycol SCHEMBL11459408 | 0.88 | HSD17B10 (0.43) | MEN1KMT2AHTTTHRBMAPT | |
| SCHEMBL8008323 | 0.87 | MEN1 (0.52) | MEN1KMT2AHTTTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014898-A1 | Water-absorptive contact lens and method of producing the same | MENICON CO., LTD. (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1378769-A2 | Water-absorptive contact lens and method of producing the same | Menicon Co., Ltd. (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-6025449-A | NEUTRALIZED; ALKYLENE OXIDE GROUP-CONTAINING (METH)ACRYLATE MONOMER; WATERPROOFING; BONDING STRENGTH | KANSAI PAINT CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| US-4194066-A | POLYMERIZING POLYOXYALKYLENE GLYCOL (METH)ACRYLATES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1980-03-18 | — | — | US | disclosed |