Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1729212 | 0.85 | PTGDR2 (0.41) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL5490703 | 0.85 | F2R (0.43) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL6543733 | 0.84 | MAPT (0.43) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL1729176 | 0.84 | MAPT (0.45) | F2RKDM4EMAPTRAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL1728797 | 0.84 | F2R (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL5486564 | 0.84 | MAPT (0.40) | F2RKDM4EMAPTRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL5483217 | 0.83 | F2R (0.42) | F2RKDM4EMAPTRAB9ANPC1 | |
| Bromide SCHEMBL1730838 | 0.83 | MEN1 (0.46) | F2RKDM4EMAPTRAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL1730949 | 0.82 | F2R (0.43) | F2RKDM4EMAPTRAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL1730958 | 0.82 | F2R (0.42) | F2RKDM4EMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |