Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 16/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730642 | 0.99 | F2R (0.39) | F2RKDM4ENPC1MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL1730319 | 0.96 | F2R (0.39) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449118 | 0.90 | F2R (0.48) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731273 | 0.90 | F2R (0.33) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449115 | 0.90 | F2R (0.42) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730230 | 0.89 | F2R (0.49) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730798 | 0.89 | F2R (0.42) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732608 | 0.88 | F2R (0.39) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449127 | 0.88 | F2R (0.43) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL14449154 | 0.88 | F2R (0.48) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-B1 | 2-IMINOPYRROLIDINE DERIVATES | EISAI R&D MAN CO LTD (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |