Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1733316 | 0.99 | F2R (0.53) | F2RKDM4ENPC1MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL5486474 | 0.96 | F2R (0.50) | F2RABL1 | |
| Bromide SCHEMBL1731685 | 0.95 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731714 | 0.91 | F2R (0.46) | F2R | |
| Bromide SCHEMBL1731426 | 0.91 | F2R (0.47) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732545 | 0.90 | F2R (0.50) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL6544951 | 0.90 | F2R (0.48) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1728726 | 0.89 | F2R (0.48) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1730681 | 0.89 | F2R (0.47) | F2RKDM4ENPC1MAPTRAB9A | |
| SCHEMBL5486476 | 0.89 | F2R (0.45) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |