Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1732738 | 0.85 | F2R (0.60) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL28740926 | 0.83 | F2R (0.56) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| Bromide SCHEMBL1731325 | 0.83 | F2R (0.56) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL1729167 | 0.82 | F2R (0.56) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| Bromide SCHEMBL5484965 | 0.81 | F2R (0.57) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL27506514 | 0.81 | F2R (0.50) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL1730995 | 0.81 | F2R (0.53) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL1730997 | 0.81 | F2R (0.53) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL1729405 | 0.81 | F2R (0.51) | F2RMAPTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL27507748 | 0.81 | F2R (0.51) | F2RMAPTSMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |