Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195582 | 0.76 | GSK3B (0.45) | GSK3BPTPN1POLB | |
| SCHEMBL5057100 | 0.74 | TSHR (0.57) | TSHRMAPK1LMNAGSK3BPOLB | |
| SCHEMBL28716033 | 0.73 | TSHR (0.39) | TSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL28716034 | 0.73 | TSHR (0.39) | TSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7859993 | 0.71 | TSHR (0.46) | TSHRMAPK1LMNAGSK3BPTPN1 | |
| SCHEMBL5050071 | 0.71 | GSK3B (0.49) | TSHRMAPK1LMNAGSK3BPTPN1 | |
| SCHEMBL28715339 | 0.71 | TSHR (0.35) | TSHRLMNAMEN1KMT2ANPC1 | |
| SCHEMBL28715340 | 0.71 | TSHR (0.35) | TSHRLMNAMEN1KMT2ANPC1 | |
| SCHEMBL5051403 | 0.70 | MAPK1 (0.63) | TSHRMAPK1GSK3BMEN1KMT2A | |
| SCHEMBL5057184 | 0.70 | GSK3B (0.47) | TSHRMAPK1LMNAGSK3BPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |