Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16612648 | 0.70 | CYP2C19 (0.39) | ALDH1A1BUB1 | |
| SCHEMBL16612564 | 0.69 | MAPT (0.39) | ALDH1A1KDM4EMAPK1BUB1 | |
| Verbenone SCHEMBL3506768 | 0.69 | TSHR (0.41) | MAPK1BUB1 | |
| Verbenone SCHEMBL12914978 | 0.69 | TSHR (0.41) | MAPK1BUB1 | |
| Verbenone SCHEMBL10615025 | 0.69 | TSHR (0.41) | MAPK1BUB1 | |
| SCHEMBL16612391 | 0.68 | LCK (0.45) | ALDH1A1KDM4EMAPK1ALOX12 | |
| SCHEMBL16612393 | 0.68 | CYP2C19 (0.41) | — | |
| SCHEMBL16612615 | 0.68 | MAPT (0.37) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL16612664 | 0.66 | NPC1 (0.43) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL16612599 | 0.66 | CYP3A4 (0.43) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212292-B1 | (-)-VERBENONE DERIVATIVES | EUPHAR GROUP SRL (IT) | 2004-01-14 | — | — | EP | disclosed |
| US-6649658-B1 | Water soluble antiinflammatory agents | EUPHAR GROUP SRL (IT) | 2003-11-18 | — | — | US | disclosed |
| EP-1212292-A1 | (-)-VERBENONE DERIVATIVES | Euphar Group S.R.L. (IT) | 2002-06-12 | — | — | EP | disclosed |
| WO-2000063159-A1 | (-)-VERBENONE DERIVATIVES | EUPHAR GROUP SRL (IT) | 2000-10-26 | — | — | WO | disclosed |