⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6544665 | 1.00 | — | — | |
| SCHEMBL3134391 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL28168136 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL190067 | 0.84 | CYP2D6 (1.00) | — | |
| SCHEMBL213024 | 0.84 | CYP2D6 (1.00) | — | |
| Ammonia Solution, Strong SCHEMBL25317379 | 0.81 | CYP2D6 (0.92) | — | |
| Hydrochloric Acid SCHEMBL10880042 | 0.81 | CYP2D6 (0.92) | — | |
| Ammonia Solution, Strong SCHEMBL25317376 | 0.81 | CYP2D6 (0.92) | — | |
| SCHEMBL16853126 | 0.79 | GABRR1 (0.46) | — | |
| SCHEMBL27578511 | 0.79 | GABRR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043755-B2 | Compositions, methods, and articles relating to in-situ crosslinking of polyamides during additive manufacturing | XEROX CORPORATION (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043755-B2 | Compositions, methods, and articles relating to in-situ crosslinking of polyamides during additive manufacturing | XEROX CORPORATION (US) | 2024-07-23 | — | — | US | disclosed |
| EP-4006080-A1 | COMPOSITIONS, METHODS, AND ARTICLES RELATING TO IN-SITU CROSSLINKING OF POLYAMIDES DURING ADDITIVE MANUFACTURING | Xerox Corporation (US) | 2022-06-01 | — | — | EP | disclosed |
| US-20220162474-A1 | COMPOSITIONS, METHODS, AND ARTICLES RELATING TO IN-SITU CROSSLINKING OF POLYAMIDES DURING ADDITIVE MANUFACTURING | XEROX CORPORATION (US) | 2022-05-26 | — | — | US | disclosed |
| US-20210188914-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| US-10954273-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190389911-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-12-26 | — | — | US | disclosed |
| US-10414801-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180222942-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-20180222942-A1 | HYBRID CYCLIC LIBRARIES AND SCREENS THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-08-09 | — | — | US | disclosed |
| US-9250237-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-9250237-B2 | Hybrid cyclic libraries and screens thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-02-02 | — | — | US | disclosed |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | THE JOHNS HOPKINS UNIVERSITY | 2014-03-13 | — | — | US | disclosed |
| US-20140073581-A1 | Hybrid Cyclic Libraries and Screens Thereof | THE JOHNS HOPKINS UNIVERSITY | 2014-03-13 | — | — | US | disclosed |
| EP-0931792-B1 | Depsipeptides containing non-natural amino acids | NISSHIN SEIFUN GROUP INC (JP) | 2004-01-07 | — | — | EP | disclosed |
| US-6288038-B1 | ACCELERATE APOLIPOPROTEIN E PRODUCTION; NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE; ANTILIPEMIC AGENTS | NISSHIN SEIFUN GROUP INC. (JP) | 2001-09-11 | — | — | US | disclosed |
| US-6252041-B1 | Depsipeptides containing non-natural amino acids | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-1028126-A1 | DEPSIPEPTIDE DERIVATIVES BEARING PIPERAZINONE RINGS | Nisshin Flour Milling Co., Ltd. (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0931792-A1 | Depsipeptides containing non-natural amino acids | Nisshin Flour Milling Co., Ltd. (JP) | 1999-07-28 | — | — | EP | disclosed |
| WO-1995023811-A1 | NOVEL CARBOCYCLIC COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION BY INTERACTION WITH THE GPIIB/IIIA RECEPTOR COMPLEX | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |