Oxyfluorfen

Oxyfluorfen

SCHEMBL6545582

C=C(c1ccccc1)c1ccccc1.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
TDP1 Q9NUW8 2/20 0.59
TTR P02766 1/20 0.59
PPOX P50336 1/20 0.59
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
FFAR1 O14842 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 2/20 0.41
MRGPRX4 Q96LA9 5/20 0.41
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL39004 0.90 MEN1 (0.65) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL29352272 0.90 MEN1 (0.65) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL8539841 0.90 MEN1 (0.65) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL11018176 0.89 MEN1 (0.64) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL11018179 0.89 MEN1 (0.64) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL9065564 0.88 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL28190722 0.88 MEN1 (0.62) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL27818003 0.87 MEN1 (0.63) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL8072583 0.87 MEN1 (0.61) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL28062505 0.86 KMT2A (0.56) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789510-B1 WETTABLE POWDER FORMULATIONS AGRICULTURE VICTORIA SERV PTY (AU) 2004-01-21 EP disclosed
EP-0789510-A4 WETTABLE POWDER FORMULATIONS DARATECH PTY LTD (AU) 2000-10-11 EP disclosed
EP-0789510-A1 WETTABLE POWDER FORMULATIONS DARATECH PTY. LTD. (AU) 1997-08-20 EP disclosed
WO-1996013975-A1 WETTABLE POWDER FORMULATIONS DARATECH PTY. LTD. (AU) 1996-05-17 WO disclosed