Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 14/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.49 |
| ▸ | SRC | P12931 | 12/20 | 0.49 |
| ▸ | SYK | P43405 | 12/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546701 | 0.95 | GSK3A (0.48) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6545669 | 0.93 | SRC (0.56) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546285 | 0.88 | GSK3A (0.51) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546533 | 0.87 | GSK3A (0.49) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546534 | 0.86 | GSK3A (0.57) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6547530 | 0.85 | GSK3A (0.53) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546490 | 0.84 | GSK3A (0.55) | GSK3AMAPK14SRCSYKCXCL8 | |
| SCHEMBL6547025 | 0.84 | GSK3A (0.60) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546644 | 0.83 | GSK3A (0.61) | GSK3AMAPK14SRCSYK | |
| SCHEMBL6546739 | 0.83 | GSK3A (0.51) | GSK3AMAPK14SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381592-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002083628-A1 | 1,4-DISUBSTITUTED BENZO-FUSED COMPOUNDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | disclosed |